Tuesday, April 30, 2013

Impax, GSK end Parkinson's disease partnership

(Reuters) - Impax Laboratories Inc said partner GlaxoSmithKline Plc ended their collaboration on Impax's experimental Parkinson's disease drug due to regulatory and launch delays in the countries in which GSK has rights to market the drug.

Impax shares fell 2 percent to $17.32 in premarket trade after closing at $17.62 on Friday on the Nasdaq.

Under a deal, GlaxoSmithKline had the right to develop and market the drug, IPX066, outside the United States and Taiwan.

Rights to the drug, which is known as Rytary in the United States, will transfer back to Impax at the end of July 2013.

Impax did not disclose the financial impact of the deal termination, if any. It said it plans to find a partner or partners for markets outside the United States.

Rytary is an extended-release capsule being developed for the symptomatic treatment of adult patients with idiopathic Parkinson's disease.

(Reporting by Esha Dey in Bangalore; Editing by Sreejiraj Eluvangal)

Source: http://news.yahoo.com/impax-gsk-end-parkinsons-disease-partnership-130735945.html

kennedy center honors boxing day george h w bush Belk Led Zeppelin Ned Rocknroll Norman Schwarzkopf

American Pets | Visual.ly

Sorry, Readability was unable to parse this page for content.

Source: http://visual.ly/american-pets

michael phelps Kerri Strug Ledecky Nadia Comaneci Rebecca Soni Snoop Lion London 2012 Table Tennis

Celebs With Big Shoes To Fill Literally: Celebrities With Huge Feet!

Celebs With Big Shoes To Fill Literally: Celebrities With Huge Feet!

Big footed celebsCelebrities can improve upon their looks with great make-up artists, plastic surgery, etc. But one part of the body that can’t be “fixed” is large feet. Let’s check out the celebrities with the biggest feet in Hollywood! Kate Winslet Kate Winslet, known for her films “Titanic”, and “Eternal Sunshine of the Spotless Mind”, wears a ...

Celebs With Big Shoes To Fill Literally: Celebrities With Huge Feet! Stupid Celebrities Gossip Stupid Celebrities Gossip News

Source: http://stupidcelebrities.net/2013/04/celebs-with-big-shoes-to-fill-celebrities-with-huge-feet-photos/

selection sunday NIT Tournament clay matthews Ncaa Tournament 2013 2013 NCAA Bracket leprechaun ides of march

Sony Xperia Tablet Z available for preorder, includes free cradle offer

Sony Xperia Tablet Z

Preorder a 32GB version in white by May 24 to qualify for a free cradle

Sony has officially started taking preorders for its newest 10.1-inch Jelly Bean tablet, the Xperia Tablet Z. This incredibly thin, IR-sporting device was announced in late January, and shown off during the Mobile World Congress. It comes with a 'Full HD Reality Display' (1920x1200p WUXGA), 1.5GHz Snapdragon S4 Pro processor with 2GB RAM, a 2MP camera up front, and an 8MP camera in the rear.

To help up-sell those considering the $499.99 16GB black model, Sony is throwing in a free cradle accessory to customers that preorder a $599.99 32GB model in white. The 32GB version comes in black as well, but for whatever reason the free accessory offer only applies to the white version. Preorders must be in by May 24 to be eligible for a free cradle.

Head over to the Sony Tablet preorder page to reserve yours. If you're still on the fence, check out our initial hands-on, as well as the subsequent hands-on of this gorgeous tablet.

Source: Sony

    


Source: http://feedproxy.google.com/~r/androidcentral/~3/hJWFFFQO8_w/story01.htm

norovirus Eclampsia Kendrick Lamar JJ Abrams New Orleans Pelicans chris brown hillary clinton

Molecular role of gene linked to blood vessel formation uncovered

Apr. 29, 2013 ? University of North Carolina researchers have discovered that disrupting a gene that acts as a regulatory switch to turn on other genes can keep blood vessels from forming and developing properly.

Further study of this gene -- a "transcription factor" called CASZ1 -- may uncover a regulatory network that influences the development of cardiovascular disease. A number of other studies have already shown a genetic link between mutations in CASZ1 and hypertension.

The UNC research, which was carried out in a frog model as well as human cells, will be published April 29, 2013, in the journal Developmental Cell.

"There has been a lot of interest in studying the vasculature because of its role in a wide range of disease states, as well as human development. But there are very few transcription factors that are known to affect the vasculature. To find a new one is quite unique, and then to be able to link it up to a known network of vascular development is surprising and encouraging," said senior study author Frank Conlon, PhD, an associate professor of genetics in the UNC School of Medicine.

During vascular development, specialized cells coalesce into three-dimensional "cords" that then hollow out to provide a path for transporting blood throughout the body. This process involves the complex coordination of molecular entities like growth factors and signaling molecules, defects that have been associated with human illnesses such as cancer, stroke, and atherosclerosis.

Conlon has long been interested in understanding how these various molecular players come together in the cardiovascular system. In 2008, his laboratory showed that a gene called CASZ1 is involved in the development of heart muscle. In this study, he and his colleagues decided to look for its role in the development of blood vessels.

Marta S. Charpentier and Kathleen S. Christine, lead authors of the study and graduate students in Conlon's laboratory, removed CASZ1 from frog embryos and looked to see how its absence affected the development of the vasculature. Without CASZ1, the frogs failed to form branched and functional blood vessels. When they removed the CASZ1 gene from cultured human cells, Charpentier and Christine saw similar defects: the cells did not sprout or branch correctly due to their inability to maintain proper adhesions with the surrounding extracellular matrix.

"If you take out CASZ1, these cultured human cells try to migrate by sending out these filopodia or little feet, but what happens is it is like someone nails down the back end of those growing vessels. They try to move and keep getting thinner and thinner, and like an elastic band it gets to be too much and just snaps back. It appears to cause an adhesion defect that makes the cells too sticky to form normal vessels," said Conlon.

CASZ1 is a transcription factor, a master switch that controls when and where other genes are expressed. Therefore, Charpentier and Christine did a series of experiments to explore CASZ1's influence on a known vascular network, involving other genes called Egfl7 and RhoA. When Charpentier and Christine added the Egfl7 gene to her CASZ1-depleted cells, the defect in blood vessel formation went away, suggesting that the two genes are connected. They then showed that CASZ1 directly acts on the Egfl7 gene, and that this activity in turn activates the RhoA gene, which is known to be required for cellular behaviors associated with adhesion and migration.

Transcription factors themselves are so essential that they are generally considered to be "undruggable," but the researchers say that further studies into how specific transcription factors work and the targets they control could eventually lead to new drug candidates.

"Egfl7 is a therapeutic target of interest, because companies such as Genentech are already working on it for cancer therapy," said Charpentier. "Figuring out how it is regulated is important not just for understanding the biology of it, but also for discovering targets that could trigger the development of innovative therapeutic strategies for cardiovascular disease."

The research was a collaboration between the Conlon, Taylor, and Bautch labs at the McAllister Heart Institute at UNC and was funded by the National Institutes of Health and the American Heart Association. Study co-authors from UNC were Nirav M. Amin, PhD; Kerry M. Dorr; Erich J. Kushner, PhD; Victoria L. Bautch, PhD; and Joan M. Taylor, PhD.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by University of North Carolina School of Medicine, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Marta?S. Charpentier, Kathleen?S. Christine, Nirav?M. Amin, Kerry?M. Dorr, Erich?J. Kushner, Victoria?L. Bautch, Joan?M. Taylor, Frank?L. Conlon. CASZ1 Promotes Vascular Assembly and Morphogenesis through the Direct Regulation of an EGFL7/RhoA-Mediated Pathway. Developmental Cell, 2013; 25 (2): 132 DOI: 10.1016/j.devcel.2013.03.003

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/fPFRSP7gyI8/130429125512.htm

nba trade thomas robinson nba trades ign Xbox 720 HTC One NICOLAUS COPERNICUS

Monday, April 29, 2013

Bangladesh owner is at nexus of politics, business

SAVAR, Bangladesh (AP) ? When the cracks in the building appeared early Tuesday afternoon, a stocky man in his early 30s, a feared political operative who a neighbor says dropped out of school in seventh grade, quickly arrived at the scene in this crowded industrial suburb of the capital.

By then, fear had spread through the 3,200 people who worked in the five clothing factories that jammed the upper floors of Rana Plaza, and the handful of shops on the lower ones. Most of the workers had gathered in the street out front. Few wanted to go back in. Inspectors said the eight-story building should be closed until it could be inspected.

But Mohammed Sohel Rana scoffed.

"The building has minor damages," Rana, the building's owner, told gathering reporters. "There is nothing serious."

The next morning, many of the building's shops and a first-floor bank remained closed. But the factories' 8 a.m. shift began as usual. About 45 minutes into the shift, the building suddenly collapsed, killing at least 350 people in a fury of falling concrete. It was the worst industrial accident in the history of Bangladesh. More than three days later, rescuers are still crawling through the wreckage, hoping to find anyone who has managed to survive so long. By Saturday, nearly all the people being carried out were dead.

Rana, though, has disappeared. He hasn't been seen, according to local media reports, since he left his basement office in Rana Plaza and drove away, just before the collapse. Today, his political patron has abandoned him and authorities want to arrest him.

Rana sits at the nexus of party politics and the powerful $20 billion garment industry that drives the economy of this deeply impoverished nation. Experts say this intersection of politics and business, combined with a minimum wage of $9.50 a week that has made Bangladesh the go-to nation for many of the world's largest clothing brands, has created a predictable danger for factory workers.

Government officials, labor activists, manufacturers and retailers all called for improved safety standards after a November fire in the same suburb, when locked emergency exits trapped hundreds of garment workers inside amid spreading flames and 112 people died. But almost nothing has changed.

"Successive Bangladeshi governments have paid lip service to worker safety but in reality it is only the factory owners who have the ear of policymakers," Brad Adams, the Asia director for Human Rights Watch, said in a statement. "How many factory tragedies will it take before the Bangladeshi government ends its cozy relationship with powerful company owners and prioritizes worker safety?"

Before the collapse, Rana was little known outside of the few blocks of his tiny empire, a grid of poorly paved streets in the crowded industrial suburb of Savar, built up over the past decade or so around hundreds of garment factories.

The son of a local businessman with political connections, Rana became a neighborhood force by working as an organizer for the two political parties that have competed for power for decades in Bangladesh, according to local politicians, as well as someone who grew up near Rana and still lives in the area.

While Rana is currently a leader of the youth group of the ruling Awami League, he has also worked for that party's archrival, the Bangladesh National Party.

"He doesn't belong to any particular political party," said Ashrafuddin Khan Imu, an Awami League leader and longtime Rana rival. "Whatever party is in power, he is there."

In essence, these people say, Rana is a neighborhood political enforcer, regularly ordering thousands of people into the streets for rallies. Most recently, Imu said, he has been working for Awami League lawmaker Talukder Touhid Jang Murad. When Murad was asked about Rana after the collapse, Murad denied any connections. The next day, Dhaka newspapers printed photographs of Murad kissing Rana on the forehead after a successful rally earlier this year.

"He used to intimidate people whenever he needed them, like bringing people out for street marches in support of the lawmaker," said the neighbor, who spoke on condition he not be named, fearing Rana would send his men to beat him up after having been threatened once before. "Neighbors would avoid him ... No one wanted to upset him."

Money came with his political connections, with wealth built upon a string of government-owned properties he acquired at reduced prices, according to local media reports. He built a small apartment building and a small commercial building, where a Bata shoe store is now on the ground floor. In 2010 he built Rana Plaza on land that had once been a swamp. He had a permit to erect a five-story building, but built three additional stories illegally.

Until Wednesday, he lived just a few blocks from Rana Plaza, in a five-story red-brick building he owns at the end of a narrow alley. The ground floor has a hand-painted medieval scene, with an aristocratic woman, or perhaps a bride, being carried by scowling bearers in a covered palanquin. The neighbor says he is married, and has two children. The buildings indicate he is a man of considerable stature locally, but is almost certainly not a member of the country's tiny elite.

After the cracks appeared in the building, witnesses say Rana quickly went to work. On Wednesday morning, he and a number of factory managers ordered nervous workers into the building shortly before the collapse, according to the neighbor, who was present at the scene, and local press reports.

"I was too afraid to go inside the building. But the factory officials assured us they would also be in the factory, so there should not be any problem," said Kohinoor Begum, a factory worker who survived but whose hands were injured.

By Saturday night, Rana was still nowhere to be found. Authorities say they detained his wife on Friday, apparently as a way to convince him to surrender.

What will happen to him? At first glance, the situation doesn't look good: He's on the run, his political allies have publicly abandoned him, Bangladesh's most powerful garment industry association says he ignored their warnings to shut the building, the prime minister has called for his arrest.

But in the streets of Savar, many people note that while three managers have been arrested in connection with the Tazreen fire, the factory owner remains free.

___

Sullivan reported from New Delhi, India. Julhas Alam in Dhaka contributed to the report.

Source: http://news.yahoo.com/bangladesh-owner-nexus-politics-business-051832391.html

minnesota twins bobby abreu 2012 draft colt mccoy arbor day mike adams janoris jenkins

1st female Iraq war resister to be court-martialed

FORT CARSON, Colo. (AP) ? A court-martial got underway Monday for the first female U.S. Army soldier to flee to Canada to avoid a second tour of duty in the Iraq war.

Army Pfc. Kimberly Rivera is charged with desertion and could face up to five years in prison and a dishonorable discharge if convicted, the Colorado Springs Gazette reported (http://bit.ly/12wpci6 ).

Rivera, 30, was a wheeled-vehicle driver in Fort Carson's 4th Infantry Brigade Combat Team and served in Iraq in 2006. She has said that, while there, she became disillusioned with the U.S. mission in Iraq.

During a two-week leave in the U.S. in 2007, Rivera crossed the Canadian border after she was ordered to serve another tour in Iraq. She applied for refugee status but was denied.

Rivera then applied for permanent residency, but Canadian immigration officials rejected that application, too. Authorities also rejected her requests to stay on humanitarian and compassionate grounds.

Rivera was first ordered to leave Canada or face deportation in 2009, but she appealed that decision. The mother of four faced another deportation order issued in 2012.

She was arrested at the U.S. border and taken into military custody.

Roughly 19,000 people signed an online petition in Canada protesting Rivera's deportation order, and rallies were held in a number of Canadian cities calling on the government to let her stay in the country.

Nobel Peace Prize winner Archbishop Desmond Tutu and the U.S. veterans organization Veterans for Peace also protested the deportation order.

In 2012, the War Resisters Support Campaign, a Canadian activist group, estimated there were about 200 Iraq war resisters in Canada. It said two other Iraq war resisters who were deported, Robin Long and Clifford Cornell, faced lengthy jail sentences upon their return.

Long was given a dishonorable discharge in 2008 and sentenced to 15 months in a military prison after pleading guilty to charges of desertion.

The lower house of Canada's Parliament passed a motion in 2009 in favor of allowing U.S. military deserters to stay, but the Conservative Party government was not persuaded.

During the Vietnam War, as many as 90,000 Americans won refuge in Canada, most of them to avoid the military draft. Many were given permanent residence status that led to Canadian citizenship, but the majority went home after President Jimmy Carter granted amnesty in the late 1970s.

Many Canadian politicians say the situation is different now because Iraq war deserters like Rivera enlisted in the U.S. military voluntarily.

Source: http://news.yahoo.com/1st-female-iraq-war-resister-court-martialed-172614435.html

neil degrasse tyson davy jones death born this way foundation lytro camera lytro camera andrew brietbart branson mo

Microsoft working on redesigns for Xbox, Yammer, Skype and Bing

Microsoft working on redesigns for Xbox, Yammer, Skype and Bing

Considering Microsoft's efforts to rebrand, redesign and rebuild its Windows platform, it's no surprise to hear the company is tweaking the visual aesthetics of its other brands, too. Speaking at Design Day 2013, Wolff Olins creative director Todd Simmons and Windows Phone design studio manager Albert Shum talked about the challenges of rebranding a company like Microsoft. "We're still trying to figure out how to put a consumer face on this brand, as an ecosystem," Simmons said, explaining how the team wanted to get away from the idea of Microsoft being a top-down, monolithic entity. The discussion touched on the creation of the Windows 8 logo, but also shed light on efforts to revamp other Microsoft brands. "Other brands are coming along too," Simmons explained, teasing the audience with a pair of sketches. "Bing, Skype, Yammer, Xbox -- everything is under development." With Microsoft's next generation gaming hardware lurking just around the corner, the time for a new logo might just be nigh. Read on to see the pair's full 45-minute presentation for yourself.

Filed under: ,

Comments

Via: Verge, Travis Lowdermilk (Twitter)

Source: Vimeo, Design Day 2013

Source: http://www.engadget.com/2013/04/28/microsoft-working-on-brand-redesigns-for-xbox-yammer-skype/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

madmen james cameron liam hemsworth miss canada justin bieber boyfriend marianas trench camille grammer

Sunday, April 28, 2013

Fire breaks out at collapsed factory in Bangladesh

SAVAR, Bangladesh (AP) -- A fire broke out late Sunday in the wreckage of the garment factory that collapsed last week in Bangladesh, with smoke pouring from the piles of shattered concrete and some of the rescue efforts forced to stop.

The fire came four days after the collapse, as rescuers were trying to free a woman they found trapped in the rubble. The flames broke out when sparks were generated by those rescuers trying to cut through a steel rod to reach the woman, said a volunteer rescuer, Syed Al-Amin Roman. At least three rescue workers were injured in the fire, he said.

Rescuers have retreated from the part of the wreckage where the fire erupted, but were still trying to reach any possible survivors in other parts of the destroyed eight-story building.

Firefighters were frantically hosing down the flames.

"Hopefully we will be able to control it," said Brig. Gen. Mohammed Siddiqul Alam Shikder, who is overseeing rescue operations.

It wasn't immediately clear what happened to the trapped woman.

The fire came hours after the owner of the illegally-constructed building was captured Sunday at a border crossing with India.

Mohammed Sohel Rana was arrested in Benapole in western Bangladesh, just as he was about to flee into India's West Bengal state, said Jahangir Kabir Nanak, junior minister for local government. Rana was brought back by helicopter to the capital Dhaka where he faced charges of negligence.

Rana's capture brought cheers and applause when it was announced on a loudspeaker at the site of the collapsed building in the Dhaka suburb of Savar.

At least 377 people are confirmed to have died in the Wednesday collapse. Three of the building's floors were built illegally. The death toll is expected to rise but it is already the deadliest tragedy to hit Bangladesh's garment industry, which is worth $20 billion annually and is a mainstay of the economy. The collapse and previous disasters in garment factories have focused attention on the poor working conditions of workers who toil for as little as $38 a month to produce clothing for top international brands.

Bangladesh's garment industry was the third largest in the world in 2011, after China and Italy, having grown rapidly in the past decade. The country's minimum wage is the equivalent of about $38 a month.

Source: http://news.yahoo.com/fire-breaks-collapsed-factory-bangladesh-165955376.html

best buy sears Aeropostale Jcpenny abercrombie abercrombie ohio state football

mobile ebook reader Mastering Business Negotiation : A Working ...

Jossey-Bass | 2006-07-21 | ISBN: 0787980994 | 320 pages | PDF | 1,2 MB

Mastering Business Negotiation is a handy resource for any leader or manager who needs practical strategies and ideas when conducting business negotiations. Grounded in solid research, the authors ? experts in the field of business negotiation ? reduce the huge volume of available information into an accessible handbook for busy executives who need to prepare for everyday negotiations as well as for more demanding and complex negotiation situations.
Mastering Business Negotiation offers down-to-earth advice for learning to play the negotiation game and shows how to:
Understand the game so you can better control what happens
Predict the sequence of negotiation activities and move from disagreement toward agreement
Identify the strategies and tactics of other players in the game.
Apply the rules of the game ? the "do?s and don?ts" that will ultimately lead to success

Download:

http://uploading.com/files/5875F1H4/MastBusNeg.rar.html

Source: http://www.99980.net/business/mobile-ebook-reader-mastering-business-negotiation-a-working-guide-to-making-deals-and-resolving-c/

my fair lady conversion disorder the chronicle spinal stenosis the forgotten man mike jones just friends

Mapping of cancer cell fuel pumps paves the way for new drugs

Apr. 28, 2013 ? For the first time, researchers at Karolinska Institutet in Sweden have managed to obtain detailed images of the way in which the transport protein GLUT transports sugars into cells. Since tumours are highly dependent on the transportation of nutrients in order to be able to grow rapidly, the researchers are hoping that the study published in the scientific magazine Nature Structural & Molecular Biology will form the basis for new strategies to fight cancer cells.

In order to be able to fuel their rapid growth, cancer tumours depend on transporter proteins to work at high speed to introduce sugars and other nutrients that are required for the cell's metabolism. One possible treatment strategy would therefore be to block some of the transporters in the cell membrane which operate as fuel pumps, thus starving out and killing the cancer cells.

One important group of membrane transporters is the GLUT family, which introduces glucose and other sugars into the cell. Glucose is one of the most important energy sources for cancer cells and GLUT transporters have been shown to play a key role in tumour growth in many different types of cancer.

In the current study, researchers from Karolinska Institutet have performed a detailed study of the way in which suger transport is executed by the protein XylE, from the Escherichia colibacterium, whose function and structure is very similar to GLUT transporters in humans. For the first time, the researchers have described the way in which the protein's structure changes between two different conformations when it binds and transports a sugar molecule.

"In showing details of the molecular structure of the region that bind the sugar, our study opens up the opportunities to more efficiently develop new substances that may inhibit GLUT transporters," says P?r Nordlund at the Department of Medical Biochemistry and Biophysics, one of the researchers behind the study. "Information on the structure of the transport protein facilitates the development of better drugs in a shorter time. Such GLUT inhibitors could potentially be used to treat cancer in the future."

The study may be of significance not just to cancer research but also in the field of diabetes. GLUT plays a key role in diabetes since insulin works by activating the uptake of glucose from the blood by means of GLUT transporters in the cell membrane.

GLUT and the studied XylE transporter belong to the very large group of metabolite transporters called the Major Facilitator Superfamily (MFS), which is important in many diseases and for the uptake of medicines in cells.

"Many aspects concerning molecular mechanisms for the function of GLUT transporters are probably common to many members of the MFS family, which are involved in a broad spectrum of diseases in addition to cancer and diabetes," says P?r Nordlund.

As well as membrane transporters, which have undergone in-depth analysis in the current study, many different membrane proteins pass through the surface membrane of the cells. Their significance to the cell function and the development of drugs has been noted before, not least through the Nobel Prizes that were awarded to researchers who used mechanistic and structural studies to map the function of two other major membrane protein families, G-protein-coupled receptors and ion channels.

The current study has been financed by grants from the Swedish Research Council, the Swedish Cancer Society, the European Molecular Biology Organization (EMBO) and The Danish Council for Independent Research.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Karolinska Institutet, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Esben M Quistgaard, Christian L?w, Per Moberg, Lionel Tr?saugues, P?r Nordlund. Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters. Nature Structural & Molecular Biology, 2013; DOI: 10.1038/nsmb.2569

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/YpfcBJy_z0w/130428144853.htm

sinkhole justin bieber Real Madrid Vs Manchester United Duck Dynasty sequestration Van Cliburn Sequester

Skagit County lakes offer variety for fishers - The Bellingham Herald

Skagit County lakes offer all the variety of recreational fishing that Whatcom County waters do, and four Skagit lowland lakes receive the same fine trout, produced at Kendall Creek and Bellingham Trout hatcheries, that Whatcom lakes do,

So whether it's a change of scenery you want, a more finicky trout that'll test skills, tastier fare for the fry pan or perhaps scarcer but bigger quarry, you'll find a selection of fishing lakes in our neighboring county to satisfy any need or desire.

When you take to the water on opening day Saturday, keep these things in mind:

- Statewide creeks, beaver ponds and most main rivers are closed to all fishing until at least June.

- To learn the specific rules for your intended lake, start on page 16 of the new 2013-14 Fish Washington pamphlet.

- Unless a different bag limit is specified in the special rules, a total of five trout per day may be kept from any lake or reservoir. Other fish species have different daily takes.

- For many lakes and reservoirs there is no minimum size for trout. However, some lakes do have trout specific length rules and other fish species may have minimum and/or maximum keeper lengths specified, too.

- Two-pole license endorsements cost $14.80, are good in many lakes and reservoirs, and allow fishers to use a second rod to catch their standard daily limit of five fish. That special revenue goes to WDFW's fish hatchery program.

? Anglers using artificial lures and flies may catch and release until they retain their daily limits. People fishing with bait may keep or release the first five otherwise legal trout they bring to hand, then must stop fishing.

? Be sure to display your WDFW vehicle access permit or Discover Pass - which is free if you buy an annual fishing license - when parking on a state fish and wildlife department access. If you are on state parks land, only the $35 Discover Pass is valid.

- While state hatchery-produced fish are safe to eat, the Washington Health Department has issued advisories for the consumption of a number of naturally spawned and/or reared fish. Lake Whatcom's smallmouth bass and perch bear such precautionary notes. See page 20 of the 2012-13 FishWashington sport regulations pamphlet.

- Check online now or pick up at any license dealer a copy of new 2013-2014 Fish Washington sport fishing pamphlet.

Some 43,200 of the more than 3 million catchable trout planted in Washington lakes by the Washington Department of Fish and Wildlife for this opener are now residing in four easily accessible lowland lakes in neighboring Skagit County.

Here's a rundown of Skagit's most popular fishing spots, leading off with its hot hatchery-stocked waters Erie, Heart, McMurray and Sixteen, for anglers seeking those obliging put and take rainbow trout.

OPENING DAY OF FISHING

This is the second in a series of three stories profiling spring trout fishing in Northwest Washington. Today, Skagit County lakes are highlighted, with many lakes opening for fishing on Saturday, April 27. Read about Okanogan County lakes Sunday, April 28. You can also find these lake profiles and maps online at Bellinglhamherald.com/outdoors.

LAKE ERIE (3)

From its nutrient-laden but shallow confines, Fidalgo Island's Erie has served up some beautiful rainbow trout - a few to nine pounds.

These trout were once grown from fingerling size, but that stocking strategy has been compromised by wintering cormorants as well as competition from illegally introduced perch.

Erie's catchable plant was boosted this sprin,g while triploid introductions have been reduced, but both will uphold Erie's reputation for fine spring season catches. Get here early and, with the crowds, plan to still-fish for a while before there's room to troll.

Season: Last Saturday, April 27, to Oct. 31. Page 60 in the regs.

Size: 111 acres.

In your catch: Rainbow trout and illegally introduced perch.

Stocking for 2013: 11,500 catchable rainbows and 850 triploid rainbows, all planted in April.

Past years' catches: Opening day kept trout averages: 3.9 in 2012, 3.4 in 2011 and 4.0 in 2010.

Angler amenities: Lake Erie Resort operates at the lake's southeast shore providing fishing tackle, ice and fee access to launch, but, alas, they don't have boats anymore.

Boat launching: WDFW, gravel with shallow drop-off. Will accommodate small trailered boats, but access has limited maneuvering room.

Boating rules: None.

Getting there: Drive west on State Route 20 from I-5 at Burlington through Sharp's Corner. Take Lake Campbell Road west from Highway 20 about two miles. Very limited off-road parking, with much spillover onto adjacent county road.

HEART LAKE (1)

Smallish Heart Lake can get just as crowded but will be no less rewarding on opening day than its neighbor to the south.

There's more shore access here in the City of Anacortes forestlands, and the bank-borne fishers do almost as well as those in stationary boats since the crowds can all but rule out trolling. Don't be surprised if a few tiny bluegill nibble at your bait. Their illegal introduction prompted the ending of young rainbow fry plants.

Season: Last Saturday, April 27, to Oct. 31. Page 61 in the regs.

Size: 61 acres, 75 percent 10 feet or less in depth.

In your catch: Rainbow trout and illegally introduced bluegill.

Stocking for 2013: 6,500 catchable rainbows in April. As with Erie, fry plants have been stopped.

Past years' catches: Opening day kept trout averages: 2.9 in 2012, 3.4 in 2011 and 4.7 in 2010.

Angler amenities: Excellent shore fishing access at the park ramp. Anglers often sit along the county road on the lake's east shore or pioneer into the park woods surrounding the lake.

Boat launching: City of Anacortes parks department, concrete puncheon ramp with shallow dropoff that will accommodate up to small trailered craft.

Boating rules: Speed limit is 5 mph, and no-wake rule is in effect.

Getting there: Take Heart Lake Road north from Lake Erie Road or drive south on Heart Lake Road from 11th Avenue in Anacortes. Some off-road parking, with spill-over onto county road.

LAKE MCMURRAY (7)

The largest hatchery-rainbow stocked lake in Skagit County, McMurray attracts a large, cosmopolitan crowd of anglers from several counties on the opener. Trolling's doable here in the lake's deeper middle section, or anglers can anchor at either end and still-fish to their heart's content.

Season: Saturday, April 27, to Oct. 31. Page 63 in the regs.

Size: 160.6 acres, maximum depth 52 feet at north central part of lake.

In your catch: Rainbow trout, native cutthroat and perhaps a landlocked salmon or two; on the warmwater ledger, perch, black crappie and largemouth bass will awaken later in the spring.

Stocking for 2013: 17,000 catchable rainbows, planted in April.

Past years' catches: Opening day kept trout averages: 3.1 in 2012, 1.6 in 2011 and 3.8 in 2010.

Angler amenities: There are several expansive but private group access areas along the lake shore if you are willing to join a fraternal or community club.

Boat launching: WDFW, graveled, but will accommodate small trailered craft. Can be crowded.

Boating rules: The lake boat speed limit is 5 mph.

Getting there: Take State Route 534 east about five miles from Conway. The public access is on the lake's south end. Parking spills over on to narrow access road out to highway.

LAKE SIXTEEN (8)

One of Skagit County's smaller "locals" lakes, Sixteen always yields good crops of imported rainbows at season's start. Discerning anglers will notice a few wild cutthroat turning up in their creels, usually the result of trolling in close to the weedy shoreline. Unfortunately, parking is limited, but under no circumstances should you park on the county road.

Season: Saturday, April 27, to Oct. 31. Page 65 in the regs.

Size: 41.6 acres.

In your catch: Hatchery rainbow predominate with some native sea-run cutthroat trout from natural spawning.

Stocking for 2013: 6,500 catchable rainbows in April.

Past years' catches: Opening day kept trout averages: 3.0 in 2012, 1.0 in 2011 and 2.0 in 2010.

Boat launching: WDFW, graveled, handles up to small trailered craft.

Angler amenities: There is some shore fishing space at ramp area. Sixteen's faithful are almost always well-mannered.

Boating rules: Gas-powered motors are banned and the lake speed limit is 5 mph.

Getting there: Take State Route 534 east from I-5 at Conway, turn left on the gravel access road. Parking space fills quickly here.

OTHER SKAGIT WATERS

Lunker triploid rainbow each up to a pound and a half will be stocked in six Skagit lakes including Campbell, Clear, Erie, Heart, Pass and Vogler.

Campbell and Clear lakes also feature warmwater species, while Pass and Vogler are the featured fly-fishing only waters in Skagit County.

Though it's actually in Island County, Cranberry Lake, just south of Deception Pass in the state park complex, is close enough to the above two Fidalgo Island waters to merit mention, especially because of its hard-to-entice brown trout.

Much sought-after kokanee are the staple in Skagit County's largest fresh- and still-water body, Lake Shannon, a Puget Sound Energy hydroelectric reservoir.

Big Lake holds middling largemouth bass, together with nice crappie that should verge on 11 inches, in its long, shallow reach. There's a limit on the sunfish, as well as a minimum size.

For more out-of-the-way angling options, try the walk-in waters of Whistle Lake south of Anacortes, as well as drive-up Grandy Lake or Texas Ponds in the Cascade foothills for cutthroat trout.

LAKE SHANNON (15)

The lower and older of the Baker River Valley's two hydroelectric impoundments north of Concrete, at one time Shannon was renowned for its prolific kokanee. With shifts in management of both PSE reservoirs and their salmon, this once hot angling spot has chilled. There's now a size limit of 6 to 18 inches on trout, and and native char (bull trout/Dolly Varden) are off limits. Opening day yields can be good for kokanee if you chum up the waters downlake near the dam's log boom. If you value elbow -room as much as hot fishing, Shannon's seven miles of water allow you to pull gang trolls to your heart's content at multiple depths for both silvers - and maybe a stump or two. With Shannon's fetch, beware of windy afternoons.

Season: Saturday, April 27, to Oct. 31. Page 65 in the regs.

Size: 2,148 acres.

Angler amenities: Some shore fishing at the launch site. The ramp is wide and graveled but the lower end is rough when the reservoir is low. As of Thursday, April 25, Shannon was at 422.3 feet above sea level and saw-tooth daily activity is around 20 feet below nominal full pool.

In your catch: Kokanee with occasional rainbow, cutthroat and eastern brook trout.

Stocking for 2013: No gamefish planted.

Past years' catches: Not available.

Boat launching: PSE and Skagit County provide launch access at old Lone Star Cement location on the lower southeast side of the lake. At lower lake levels the ramp can be rough.

Boating rules: No boats inside log boom at dam. Also, the east bank will be closed due to construction of the fish out-migration facility.

Getting there: From Interstate 5, take Cook Road east to Sedro-Woolley, then continue east on Highway 20 to Concrete. Cross the Lowell Peterson Bridge and take the next left turn, take another left at the stop sign and then the uphill right before crossing the old bridge. This will take you to either the dam or past Everett Lake to the power-line right-of-way and the left turn downhill to the launch.

VOGLER LAKE (14)

Its fly fishing-only waters make Volger a fair bet for a spring venture - if you don't mind a quiet, catch and release experience with some potential for having your arms tugged out of their shoulder sockets.

Season: Saturday, April 27, to Oct. 31. Page 67 in the regs.

Size: 3.5 acres, maximum depth 10 feet.

Angler amenities: Catch and release under the fly-fishing rule but not two poles. Vogler is shallow and warms quickly, so skip it during the hot summer. Do try it again in October before the closing.

In your catch: Rainbow trout.

Past years' catches: No creel info.

Stocking for 2013: 200 catchable rainbow in April 2013 and 59 triploid rainbows in May.

Boat launching: WDFW, graveled with capacity for small trailered boats, carry-ins and certainly belly boats.

Boating rules: None.

Getting there: Take Cook Road east from I-5 to Sedro-Woolley. Continue east on Highway 20 past Hamilton, turn left on Baker Lake Road and drive past Grandy Lake to Burpee Hill Road. Turn right and go to the top of the hill (about a half mile).

CAVANAUGH LAKE (13)

About the size of Lake Samish, out-of-the-way Cavanaugh has long been considered a summer-home-by-the-lake type of place. It's open year-round and among its principal historical yield have been both cutthroat trout and kokanee, though the "silvers," as the kokanee are called, are small. You'll also find rainbows (excess hatchery program trout), some holdover cutthroat trout down deep, an occasional eastern brook and a few largemouth bass. Sorry, there won't be any triploid rainbows this year. You may chum or feed for kokanee when still-fishing.

Season: Year-round. Page 59 in the regs.

Size: 844 acres, maximum depth 80 feet just east of islands.

Angler amenities: Best fished now before the weather and water warm when the skier/skidoo set starts churning up the lake. Try fishing deep for the cutthroat.

In your catch: Rainbow and cutthroat trout, kokanee (land-locked sockeye salmon), eastern brook trout and occasionally largemouth bass.

Past years' catches: No creel info.

Stocking for 2013: 10,152 cutthroat fry in June 2012; 21,200 rainbow fry from June to October 2012; and 39,198 kokanee fingerlings in December 2012.

Boat launching: WDFW, graveled on the southeast side of the lake, best approached by taking the lake-shore drive around the southwest side of the lake.

Boating rules: None.

Getting there: Drive from I-5 to Highway 9 somewhere around Mount Vernon and drive south along the east side of Big Lake and watch for the Lake Cavanaugh Road. It's about 14 miles of blacktop road, though it'll seem you're driving deep into the woods .

CLEAR LAKE (11)

For the better part of its sport-fishing existence, Clear Lake's shallows have been a spiny ray haven with an occasional load of legal rainbow trout added when state hatcheries had leftovers. Now its gets a dose of cutthroat trout fry for early spring action and a helping of triploid rainbows to break up the late spring monotony for trout anglers. It's open year-round, so the trout when active are fair game any time. Bass clubs pay attention to Clear Lake spring and fall, so spinnerbaits now or top-water lures mid-summer may be worth carrying.

Season: Year-round. Page 16 statewide rules in the regs.

Size: 223 acres. About half the lake is 20 feet or deeper to 44 feet.

Angler amenities: There is some shore fishing from the ramp causeway that juts into the lake.

In your catch: Cutthroat and rainbow trout as well as largemouth bass, yellow perch and brown bullhead catfish.

Past years' catches: No creel info.

Stocking for 2013: 9,600 cutthroat fry in fall 2012, plus 718 triploid rainbows in April 2012.

Boat launching: WDFW, located on the north side of the lake off Old Day Creek Road.

Boating rules: The speed limit is 25 mph and personal watercraft are banned on the lake.

Getting there: Take Cook Road east to Sedro-Woolley, then drive south across the Skagit River on Highway 9 to Clear Lake, turn east on Old Day Creek Road.

WHISTLE LAKE (2)

Though a walk-in lake, Whistle is not way up in the backcountry. It's on Fidalgo Island within the City of Anacortes's unique community forest lands. It's best fished in the early spring and late fall. In between it's a swimming hole.

Season: Year-round. Page 16 statewide rules in the regs.

Size: 29.7 acres.

Angler amenities: Fishing activity is limited by the steep, brushy nature of the shoreline combined with the half-mile walk. Casting spot accesses are available at intervals off the circum-lake trail. There are likely to be some good sized cutts and perhaps some fair size bass here.

In your catch: Cutthroat trout, largemouth bass and yellow perch.

Past years' catches: No creel info.

Stocking for 2013: Cutthroat trout fry in 2009 and 2012. Regular fry stocking has resumed.

Boat launching: Carry-in craft only, though the road, turned trail, is relatively flat and wide.

Boating rules: No city ordinances.

Getting there: Drive west on Highway 20 from I-5 at Burlington through Sharp's Corner, taking the Anacortes route. At Commercial Street and Highway 20, drive south on Commercial to Fidalgo Ave, turn right go one block to O Avenue. Turn south on O Avenue to a left turn onto Spradley Road. Drive east to Whistle Lake Road, then a right to the city forest lands gate.

LAKE CAMPBELL (4)

An annual stop on several Northwest bass tournament trails, Campbell hosts some championship largemouth bass and, though they don't figure in any weigh-ins, lunker rainbows thanks to the triploid program. Fishing rules also set a minimum 9-inch size and 10-fish daily limit for Campbell's crappies.

Season: Year-round. Page 59 in the regs.

Size: 410 acres.

Angler amenities: Fish it shallow. The deepest part of Campbell is a postage stamp-sized hole 16 feet deep immediately to the south of the island. Campbell's average depth according to state ecology department information is 8 feet.

In your catch: Largemouth bass, yellow perch, black crappie, bullhead catfish, cutthroat trout and some bigger specimens of channel catfish and rainbow trout.

Past years' catches: No creel info.

Stocking for 2013: 21,200 cutthroat fry from June to October 2012 and 1,071 triploid rainbow in April 2013.

Boat launching: WDFW, a concrete puncheon ramp that accommodates larger trailered boats.

Boating rules: No county ordinances.

Getting there: Drive west on Highway 20 from I-5 at Burlington through Sharp's Corner. Take Lake Campbell Road west from Highway 20 about a half mile.

PASS LAKE (5)

Its angling faithful credit the catch-and-release and fly-fishing-only rules, plus close monitoring, for creation of what is considered by many to be among the best year-round trophy coldwater-type fisheries in Northwest Washington. The average trout size is 15 inches with some ranging to 30 inches. At only 20 feet deep, these waters warm to summe time highs that can make trout lethargic, so fishing is best in fall to early/mid-spring.

Season: Year-round. Page 64 in the regs.

Size: 98 acres.

Angler amenities: The trout here speak for themselves.

In your catch: Brown, cutthroat, rainbow trout, green sunfishes and maybe red-side shiners,

Past years' catches: No creel info.

Stocking for 2013: 5,280 brown trout fingerlings in fall 2012, 10,000 rainbow fry in May 2012 and 162 triploid rainbows in May 2013.

Boat launching: WDFW, graveled ramp that accommodates up to smaller trailered boats.

Boating rules: Motors are not allowed, by WDFW regulation.

Getting there: Drive west on Highway 20 from I-5 at Burlington through Sharp's Corner. Continue west on Highway 20 to Pass Lake along highway one mile before Deception Pass Bridge.

CRANBERRY LAKE (6)

Tempered by the marine environment, unlike many other year-round waters, Cranberry Lake provides action 12 months of the year. While rainbows, including some nice carryovers, are the norm in fall and winter months, brown trout and bass tend to perk up in late spring. State park lands ring these shallow waters and help meter access.

Season: Year-round. Page 16 statewide rules in the regs.

Size: 128 acres. Half the lake is 15 feet or shallower, maximum depth is a 25-foot pocket against the north shore.

Angler amenities: A public dock in park on east side of lake, plus several extensive rock outcrops along the road on the north shore.

In your catch: Brown and rainbow trout, plus yellow perch and largemouth bass.

Past years' catches: No creel info.

Stocking for 2013: 3,000 catchable rainbows in spring 2013, and 5,280 brown trout fingerlings in fall 2012.

Boat launching: State parks (Discover Pass), gravel, accommodates car-topper and small trailered boats,

Boating rules: Internal combustion motors are not allowed by state park rule.

Getting there: Drive west on Highway 20 from I-5 at Burlington through Sharp's Corner. Continue driving west on Highway 20 to Deception Pass. Look for state park entrance about one mile south of the pass bridge.

BIG LAKE (9)

Known principally as a warm-water haunt, Big is another of Northwest Washington's shallow lowland waters that regularly hosts bass angling contests. Because of extensive residential development on its shores, aquatic activities have significantly transitioned away from fishing. Minimum size (9 inches) and 10-fish daily limit are in place for the crappie.

Season: Year-round. Page 58 statewide rules in the regs.

Size: 545 acres.

Angler amenities: Look for natural, weedy transitions of the shoreline at the very south end. Despite its lanky fjord-like appearance, Big's maximum depth is only 23 feet with an average of 14 feet.

In your catch: Largemouth bass, yellow perch and brown bullhead, plus some nice black crappie with an occasional naturally produced cutthroat trout.

Past years' catches: No creel info.

Stocking for 2013: None.

Boat launching: WDFW, dual concrete puncheon accommodates larger trailered boats.

Boating rules: None.

Getting there: Drive east from I-5 on state Highway 538, then south on state Highway 9 from Big Rock about three miles to West Big Lake Drive. Turn left and drive along the west shore of the lake to the 19000 block and the public access.

BEAVER LAKE (10)

If you are looking for a little change of pace in your warm-water fishing, try this out-of-the-way, weed-lined pan in the Nookachamps River basin. It produces fair largemouth bass, plus lots of crappies and perch during the hot summer.

Season: Year-round. Page 16 statewide rules in the regs.

Size: 73 acres, 10 feet or less of depth.

Angler amenities: If you like fishing poppers among the lily-pads, there is plenty of that habitat here.

In your catch: Yellow perch, black crappie and largemouth with an occasional cutthroat trout.

Past year's catches: No creel info.

Stocking for 2013: None.

Boat launching: WDFW, gravel, accommodates car-topper and small trailered boats.

Boating rules: None.

Getting there: From I-5, take Cook Road east to Sedro-Woolley, then drive south across the Skagit River on Highway 9 through the town of Clear Lake, turn left onto Beaver Lake Road and drive 11/2 miles southeast to Beaver Lake.

GRANDY LAKE (13)

A local's lake on a heavily driven road, but not on angler radars. Grandy's once resilient naturally reproducing cutthroat trout population has faded in the face of angling pressure and the presence of largemouth bass. A smattering of hatchery rainbows have been added. This is a combination fishing and overnight camping destination that's great for kids.

Season: Year-round. Page 16 statewide rules in the regs.

Size: 56 acres.

Angler amenities: Lakeshore county parks campground provides a one-stop fishing/camping opportunity.

In your catch: Native resident cutthroat trout and largemouth bass.

Past years' catches: No creel info.

Stocking for 2013: 1,500 catchable rainbows in spring 2013.

Boat launching: Skagit County parks, graveled, accommodates car-topper and small trailered boats.

Boating rules: None.

Getting there: From I-5, take Cook Road east to Sedro-Woolley, continue east on Highway 20 to Birdsview. Turn left onto Baker Lake Road and drive northeast five miles to Grandy Lake.

TEXAS PONDS (16)

Being out-of-the-way waters on a forest road, Texas Ponds makes for a nice, day-long outing in the woods. Though its fish see a lot of angling pressure, it's on an annual stocking list, so there are always trout available.

Season: Year-round. Page 16 statewide rules in the regs.

Size: 6 acres.

Angler amenities: Several campsites in wooded area. Ponds are in an hour-glass shape and there are some bank fishing spots along the shore in the woods.

In your catch: Cutthroat trout.

Past years' catches: No creel info.

Stocking for 2013: Stocked with cutthroat fry in 2011.

Boat launching: USFS, carry-in boats only.

Boating rules: None.

Getting there: From I-5, take Highway 20 east to Rockport, then drive south on state Highway 530 south across the Sauk River bridge to the Christian Camp Road. Turn right, drive uphill to Forest Service Road 2811. Turn left, continue uphill to ponds.

Source: http://www.bellinghamherald.com/2013/04/27/2984890/skagit-county-lakes-offer-variety.html

Club Penguin Espn Bracket First Day Of Spring 2013 Suki Waterhouse dancing with the stars Bates Motel Michelle Shocked

Rep. Mike Rogers: 'Some Action Needs to be Taken' on Syria (ABC News)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/302174096?client_source=feed&format=rss

nike foamposite galaxy bill maher seabiscuit dingo nba all star weekend malin akerman jeff carter

Kathie Lee Gifford Stands Up for Matt Lauer

Source: http://www.thehollywoodgossip.com/2013/04/kathie-lee-gifford-stands-up-for-matt-lauer/

dark knight rises trailer dark knight rises trailer vince young vince young evan longoria john edwards conocophillips

An alarm to ?Flip? over

Chances are you have more alarm clocks than uses for them.? They’re on just about every mobile electronic device you own on top of what’s currently sitting at your bedside.? If you’re the type of person who doesn’t want to navigate a bunch of menus or slide the correct buttons just to wake up at [...]

Source: http://the-gadgeteer.com/2013/04/26/an-alarm-to-flip-over/

MBTA Fox News Live Boston lockdown jennifer love hewitt 4/20 boston Cnn Live

Ukraine says too early to consider pardoning Tymoshenko

MOSCOW (Reuters) - Ukraine's presidential pardon commission said on Saturday it was too soon to consider pardoning Yulia Tymoshenko, the president's main political rival whose continuing detention is a major obstacle to improved ties with the West.

The commission said that as some criminal charges against Tymoshenko were still being investigated and the courts had not yet ruled, the "issue of her pardon is premature."

On Thursday, foreign ministers of several EU countries visited Ukraine and said there was unlikely to be rapid progress on free trade and political association deals, citing the Tymoshenko case as a major obstacle.

Tymoshenko was sentenced to seven years in prison in October 2011 for crimes related to a 2009 gas deal with Russia which Yanukovich says saddled Ukraine with exorbitant energy prices.

Since last May, Tymoshenko, who served twice as prime minister before narrowly losing the 2010 presidential run-off to Yanukovich, has been receiving treatment for back trouble in a state-run hospital in the city of Kharkiv.

Yanukovich himself says he cannot order her release because Tymoshenko is due to be tried on tax evasion and embezzlement charges and is being investigated in a murder case. She denies all the charges.

(Reporting by Katya Golubkova; Editing by Robin Pomeroy)

Source: http://news.yahoo.com/ukraine-says-too-early-consider-pardoning-tymoshenko-141529303.html

bent new york jets etch a sketch romney sean payton saints bounty program toulouse france ny jets

Saturday, April 27, 2013

These Award-Winning Vines Are Everything a Six Second Film Should Be

Vines aren't exactly the newest from of high art. But while poorly edited Vine's of your friends' cats doing nothing are probably what you see most often, there are some pretty good ones, with a bit more meat to 'em. These Tribeca Vine Competition winners are a pretty good sample. They're so good you might even go "huh!" More »
    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/-dE2Itrn1Xk/these-award+winning-vines-are-everything-a-six-second-film-should-be

the Grammys 2013 State of the Union 2013 katy perry Rihanna Katy Perry Grammys 2013 taylor swift taylor swift

NKorea says it will indict American citizen

PYONGYANG, North Korea (AP) ? North Korea said Saturday it will soon put a detained American on trial for allegedly trying to overthrow the government, further complicating already fraught relations between Pyongyang and Washington.

The indictment of Kenneth Bae comes in the middle of a lull after weeks of war threats and other provocative acts by North Korea against the U.S. and South Korea. It has expressed rage over U.N. sanctions over a February nuclear test and ongoing U.S.-South Korean military drills, though analysts say Pyongyang's motive is to get its Korean War foes to negotiate on its own terms.

"For North Korea, Bae is a bargaining chip in dealing with the U.S. The North will use him in a way that helps bring the U.S. to talks when the mood slowly turns toward dialogue," said Koh Yu-hwan, a professor of North Korean Studies at Seoul's Dongguk University.

Bae, identified in North Korean state media by his Korean name, Pae Jun Ho, is a tour operator of Korean descent who was arrested after arriving with a tour on Nov. 3 in Rason, a special economic zone bordering China and Russia.

He is the sixth American detained in North Korea since 2009. The other Americans were eventually deported or released after high-profile diplomatic interventions, including some involving former Presidents Bill Clinton and Jimmy Carter.

"The preliminary inquiry into crimes committed by American citizen Pae Jun Ho closed," the official Korean Central News Agency said in a brief report. "In the process of investigation he admitted that he committed crimes aimed to topple the DPRK with hostility toward it. His crimes were proved by evidence."

DPRK is the acronym for the North's official name, the Democratic People's Republic of Korea.

Under North Korea's criminal code, terrorist acts include murdering, kidnapping and injuring the country's citizens can lead to a death sentence or life in jail.

North Korea and the United States fought the 1950-53 Korean War and still don't have diplomatic relations. The Swedish Embassy in Pyongyang represents the United States.

KCNA didn't say when Bae's trial will take place or what the charges were.

North Korea's state media and the U.S. government have made little information about Bae public.

But his friends, colleagues and South Korean activists specializing in North Korea affairs said Bae is a Christian missionary based in a Chinese border town who frequently made trips to North Korea to feed orphans there. It is not known whether he tried to evangelize while in North Korea.

Officially, North Korea guarantees freedom of religion. In practice, authorities crack down on Christians, who are seen as Western-influenced threats to the government. The distribution of Bibles and secret prayer services can mean banishment to a labor camp or execution, defectors from the country have said.

In 2009, American journalists Laura Ling and Euna Lee were arrested and sentenced to 12 years of hard labor for trespassing and unspecified hostile acts. They were freed later that year after former President Bill Clinton visited Pyongyang to negotiate their release.

Meanwhile, South Korea is pulling its citizens from a joint factory park in North Korea after Pyongyang rejected Seoul's demand for talks on the inter-Korean symbol of detente on Saturday. The park was shuttered earlier this month after the North pulled its workers out of it, objecting to views in South Korea that the complex is a source of badly needed hard currency for Pyongyang.

__

Associated Press reporter Sam Kim contributed from Seoul, South Korea.

Source: http://news.yahoo.com/nkorea-says-indict-american-citizen-031457146.html

fourth of july IFE Fireworks 2012 4th Of July independence day BET Awards 2012 declaration of independence 4th Of July 2012

Big K.R.I.T. Reaches Out To Spike Lee To Direct New Video, Gets A Response

FROM MTV NEWS If you caught this week's episode of "RapFix Live," you saw what may be the start of a beautiful working relationship. Big K.R.I.T. sat down with Sway to talk about some recent tweets the artist had sent out to director Spike Lee. K.R.I.T. desperately wants Lee to direct the video for his [...]

Source: http://moviesblog.mtv.com/2013/04/26/big-krit-spike-lee/

helicopter crash matt jones whitney houston in casket photo resolute national enquirer whitney houston casket photo jk rowling qnexa

Square Hires Former Google SMB Of Global Sales and Operations ...

Square has announced the hiring of a new Business Lead, Francoise Brougher, and she comes straight from spending eight years at Google. For the past three years, Brougher held the title of SMB Global Sales and Operations for the online advertising unit at Google.

Although Square has grown its footprint considerably, in part because of its high-profile partnership with Starbucks, the company has yet to announce its plans to address the international market. Today, the service is only available in the U.S. and Canada, which has allowed a plethora of competitors to thrive overseas, especially in European markets where companies like?iZettle,??SumUp,Payleven,?mPowa?and Intuit?have already launched.

Here?s what Square co-founder and CEO Jack Dorsey had to say about the hiring:

Francoise is a perfect fit for Square. Her accomplishments in growing and managing large, global teams, and her focus on building simple, scalable solutions that empower millions of people, will have a huge impact on our company and our customers.

According to Brougher?s LinkedIn page, she had a hand in advertising operations for all of Google?s online advertisers, policy, quality and ad approvals as well as working on fraud and risk. These are skills that are going to come in handy for Square?s payment processing team.

Brougher?s reason for leaving Google and joining Square is to spend time helping small businesses ?find the tools they need to grow and be successful.? She went on to thank her former colleagues at Google for ?what we?ve achieved together.? Broughner played a huge role in bringing in advertisers to the system very early on, which now counts for revenue that allows Google to build out all of its moonshot ideas. She?ll be helping Square with customer support and partnerships, in addition to growing out the company internationally.

Prior to Google, Brougher spent four years at Charles Schwab as Vice President of the Business Strategy group.


Square is making commerce easy for everyone. Starting with a free credit card reader for the iPhone, iPad, and Android devices, Square Reader allows anyone to accept credit cards anywhere, anytime, for a low transaction rate of 2.75 percent per swipe, with no hidden fees. Square Register serves as a full point-of-sale system for businesses to accept payments, manage items, and share menu and location information. Square Wallet, available in the US, is the most seamless way to pay,...

? Learn more

Source: http://techcrunch.com/2013/04/25/square-hires-former-google-smb-of-global-sales-and-operations-francoise-brougher-as-business-lead/

wiz khalifa and amber rose oh the places you ll go blunt amendment justin bieber birthday read across america vikings stadium breitbart dead

Poor parenting -- including overprotection -- increases bullying risk

Apr. 25, 2013 ? Children who are exposed to negative parenting -- including abuse, neglect but also overprotection -- are more likely to experience childhood bullying by their peers, according to a meta-analysis of 70 studies of more than 200,000 children.

The research, led by the University of Warwick and published in the journal Child Abuse & Neglect, found the effects of poor parenting were stronger for children who are both a victim and perpetrator of bulling (bully-victims) than children who were solely victims.

It found that negative or harsh parenting was linked to a moderate increase in the risk of being a 'bully-victim' and a small increase in the risk of being a victim of bullying. In contrast, warm but firm parenting reduced the risk of being bullied by peers.

The study authors, Professor Dieter Wolke, Dr Suzet Lereya and Dr Muthanna Samara, called for anti-bullying intervention programmes to extend their focus beyond schools to focus on positive parenting within families and to start before children enter school.

Professor Wolke said: "The long shadow of bullying falls well beyond the school playground -- it has lasting and profound effects into adulthood.

"We know that victims and bully-victims are more likely to develop physical health problems, suffer from anxiety and depression and are also at increased risk of self-harm and suicide.

"It is vital we understand more about the factors linked to bullying in order to reduce the burden it places on the affected children and society.

"People often assume bullying is a problem for schools alone but it's clear from this study that parents also have a very important role to play.

"We should therefore target intervention programmes not just in schools but also in families to encourage positive parenting practices such as warmth, affection, communication and support."

The study categorised behaviours such as abuse/neglect, maladaptive parenting and overprotection as negative parenting behaviour.

It categorised authoritative parenting, parent-child communication, parental involvement and support, supervision and warmth and affection as positive parenting behaviours.

Professor Wolke highlighted the finding that overprotection was linked to an increased risk of bullying.

"Although parental involvement, support and high supervision decrease the chances of children being involved in bullying, for victims overprotection increased this risk.

"Children need support but some parents try to buffer their children from all negative experiences.

"In the process, they prevent their children from learning ways of dealing with bullies and make them more vulnerable.

"It could be that children with overprotective parents may not develop qualities such as autonomy and assertion and therefore may be easy targets for bullies.

"But it could also be that parents of victims become overprotective of their children.

"In either case, parents cannot sit on the school bench with their children.

"Parenting that includes clear rules about behaviour while being supportive and emotionally warm is most likely to prevent victimisation.

"These parents allow children to have some conflicts with peers to learn how to solve them rather than intervene at the smallest argument."

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by University of Warwick, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. \ Suzet Tanya Lereya, Muthanna Samara, Dieter Wolke. Parenting behavior and the risk of becoming a victim and a bully/victim: A meta-analysis study. Child Abuse & Neglect, 2013 DOI: 10.1016/j.chiabu.2013.03.001

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/mind_brain/child_development/~3/-9amG3HR3LE/130425214005.htm

jeremy lin game winner chocolate covered strawberries shrimp scampi kate upton si cover lobster recipes hearts flower delivery